Rule of thumb: cold air is at the bottom, warm at top. So try to vent out your warm air from the top. Your power supply (usually at the top of the case) should be doing that; the ATX standard has the ps blowing out, and a good ps will also have an inside intake fan to help it (which will be near the cpu).
An intake at the bottom front (blowing in) will make sure that air gets though the entire case and exits out the back top. I broke my own rule, as I have a good fan (designed for servers) blowing in from the bottom back (onto my video card), and two outflow fans (one in the power supply, and one at the very top of the case). It works so well I took out my ducted 120mm intake fan that used to blow on my T-bird (and sounded suspiciously like a vacuum cleaner). You have to be careful when you do stuff like this that there aren't "dead" spaces where air doesn't circulate over components.
When you get into overclocking, you will have fun putting fans all over the place, at least until you want more speed and get into water cooled.