Depends on how its prepared. If you boil the meat, or slow cook it, even the toughest beef can be made to fall apart on your fork, esp pressure cooked.
If your grilling, you can't beat the tenderness of Filet Minon, or my personal Fav a Fat Ribeye.
How the meat is cut makes a difference, as well as how much its cooked. MW-W will always seem more tough, than MR-R.