Nice choice in mb....that's what I put in my wife's computer, running a 3600X.
As far as Mystic Light and Dragon Center....hers doesn't have anything loaded. She couldn't care less if any RGB is on or not or what it looks like...her case is sans window, so can't see any of it, and she is happy about that.
On the other hand, my computer has an MSI MEG X570 ACE and I do have the Dragon Center for operating Mystic Light (Win 10)...mostly to shut off RGB stuff that irritates me.
And I guess since I've got nothing else loaded with Dragon Center, it appears to be causing no issues whatsoever for me.
On the other hand, there is a separate Mystic Light 3 download, but MSI states it's only for users of Win 7/8. Seems Win 10 requires(?) Dragon Center to make ML work? Don't have the answer to that, but if you're willing to try ML3 out and see if it works, the link to it is below:
Get hyped with the glowing vibes! Check out MSI Mystic Light compatible products and build the light-synchronized RGB gaming pc of your own.
us.msi.com
Myself, I'm leaving Dragon Center installed as it seems to be no problem...no crashes, no lockups, etc., just runs my ML.
Good luck!