I am currently running two Shimean 27" 2560x1440 Korean monitors with DVI input only. Originally I had both hooked up to a XFX 7970. One to the DVI dual link and one to an active mini-displayport adaptor. While this worked most of the time. It was not ideal. I had numerous issues with the active adaptor (it was an AMD "approved" model too). Issues were things like monitor on adaptor not coming back from sleep unless I rebooted, or other similar just-enough-to-piss-one-off type stuff, plus the fact you loose a USB port.
Since I never gamed on the second monitor, my solution was to put in a 2nd passive cooled 1GB 5450 video card and plug the 2nd Shimean monitor into its' d/l DVI output while leaving the other plugged into the 7970's d/l DVI. This has worked well, with one remaining issue whereas every once in a while, Windows 7 will pop a screen error saying something about running out of video memory on the 5450 and disabling Aero on the desktop depending on the application I use (generally happens with VLC player). This is a known issue with running two AMD video cards. It's not actually running out of video card memory, because it occasionally gives the same error, even when I tried using a spare 6870 card with 2GB as the second card (was too noisy though with both a 7970 and a 6870, so went back to using the 5450 with the 7970). Not sure if the new 13.1 driver fixed this random win7 aero disabling issue.
If I had to do it over again with these two particular monitors that only do DVI input, I would just get a good NVidia card with two d/l outputs since none of the AMD cards seem to have two d/l DVI ports. I have a old GTX480 in another PC that can run both monitors through its two d/l DVI outputs just fine without all the problems. Not worth the hassle with the AMD cards with the active displayport adaptors since they aren't cheap (mine cost like $90) and the adaptors suck. Now if the monitor has other inputs other than just DVI like mine do, the 7970 card might work better, but if you have two high-rez DVI-only monitors and you only want to use one video card, I'd suggest you go NVidia with two d/l DVI outputs already on the card instead of attempting the adaptor BS.