Yes, but even when I know I'm right, I tend not to continue the argument.
Like today, someone brought up genetics and I said we should put more resources into genetics because certain genes help reduce the rate of aging, and we could develop life extension. Somone else (religious) said we shouldn't play God and it could create problems later. I could have said that there are ways to genetically engineer people without altering their offspring, I could have attacked the begging the question "playing God" card, and I could have noted that even if stuff didn't work for the person completely, the alternative is old age and I'm pretty sure that has it's own problems.
But I just let the topic go.