I can tell you what happened when my ASUS gtx280 reached 115 Celcius while playing World in conflict. I had manually set the fanspeed in 100% in smartdoctor.
I played with earphones when I noticed kind of ingame lagging. I removed the earphones,
and noticed the soundlevel from the pc /card was changed.
Ok...in SmartDoc the fan was 0%, indicator showed 115 celsius, so did the GPU-Z log I had running in the background.
I had too reboot windows to get the fan working again, temp raised to about 80 celsius on idle with 0% fan before I rebooted.
The GPU Z log showed temp clearly raising from app. 90-95 degrees, while gaming and fan was working, and then in seconds up to 115, down to 110, up to 115 down to 108 celsius before I turned pc off, and rebooted.
From The GPU Z log I could see the MHz of the proscessor was downed a few steps. I can post log if anybody like to see it.
Card worked normally as I could see after reboot, also fan manually set in SmartDoc. I do belive i checked the "enable overheat protection" in smartDoc. I think smartDoc has a bug Issue, related to the fan stopping all suddenly, but I don\t know.
Crysis gave me BSOD after a few minutes, overheting I guess - also on on air. Temps while playing 100% fan enabled at 100 - 105 (!) celsius.
When on water, with a EK Fullblock, Temps raised slowly to 90 deg. C, and also over 100 in hefty ingame graphic. Temps quickly downed to 38-37 idle, 30-40 seconds after end gaming. App 20 deg. C in room. I use a Feser triple Rad and only cooling card in the loop.
The card is now returned to the shop, to let them test it out due to overheat. Hope to get a new one.......