Do I have to change the BIOS settings if I change my RAM (different timings)?

[Helicobacter]

I currently have
http://www.newegg.com/Product/Produc...82E16820145590
in my system.
The motherboard is the first Gigabyte MB that came out with the launch of the Core 2 Duo processors (DS3, I think).
Now, I want to get 2x2GB.

1. If I get 4-4-4-12, will it be supported?
2. If I get 4-4-4-12, will I have to change BIOS settings?

 

[WaTaGuMp]

Sometimes memory needs to be set manually sometimes it doesn't. Better to install and check it.

 

[Helicobacter]

Then I'd rather get the same timings. I don't like messing with the BIOS.