To answer your question.
I doubt you want VGA and S-video, unless you are making movies or something.
The answer is yes. You can get VGA and DVI (both) on many laptops.
I use two monitors with my laptop all the time, one via DVI and the other VGA.
However, on some laptop you need a docking station to get the DVI out.
One of the pannels will be a mirror of what you have on the laptop screen. However since the screen is so small compared to my LCDs I just keep it closed.
Dell lattitude D800/D810, Precision M60/M70 and Thinkpad T42/43 and R51/R52, toshiba Tecra's are all examples of notepads that support DVI, IF you have the docking station.
The Dell 9300/XPS-2 and Acer 8103/8104 support DVI and VGA without a docking station.
I run dual monitor with both ATI and NVIDIA cards. For some reason I prefer the NVIDIA dual head drivers over ATI's.