I also haven't seen where it helps get more of an oc, but it many instanances some chipset during high fsb ocing may effect that items ability to function properly as well as possibly give some instability issues.
Older i845d mobo had some issues with high fsb and usb devices either not being detected, working, or freezing of pc when connected....some chipsets with onboard video since it isn't connected to the bus may not be locked when an agp/pci lock is anabled and thus could take the effects of ocing...onboard sound has known to be an issue on some boards and cause some quality issues....Also I think I heard of some possible raid issues which can be sizeable but I don't know if the large influx of agp/pci locks on later mobo models have corrected those issues. HIgh pci clocks usually caused issues with onboard raid controllers more so then a standalone of the same controller.
Hope this helps....