There is some difference, but not significant unless your an overclocker or speed freak.
The first module allows 400DDR @ 2-3-3-?-1T memory times. This is the lesser XMS version
The second allows 400DDR @ 2-2-2-6-1T. These are faster memory settings and is the 'faster' XMS version you'll notice these are more expensive.
There is a third version that is the twin series. These are hand picked and tested pairs of modules that will run at the highest memory settings for Hyperthreading or TwinBank and such.
All of these are smoking fast. I have no idea how much of a differnce it makes going to the slightly faster memory settings.
I can say that the difference on my old Athlon 1.4 with "normal" PC2100 Crucial and faster Samsung (similar to Corsair) memory was a mild FSB OC of 145/290 and a nice FSB OC over 160/320 or so. I had to underclock my CPU as it wasn't even a paly. This was on an Epox 8k7a board, so this is not new stuff.
Hope I got this right and this helps. One of the experts if they are willing might even chime in to explain the timings which I have little clue about.