There are potential problems with every build. Like rise4310, I've done more than 1 build with the DFI and both are running perfectly. This was way back in Jan/Feb and the word wasn't out that Corsair Value ram didn't play well with the DFI. So, I did have to do some tweaking-- i.e. had to only use 1 stick of ram to get XP to install, then was able to install the other stick after... yet the other build did not have this problem... odd.
Since then, though, both builds are running perfectly, with the Corsair VS ram that everyone said just flat out doesn't work with this board.
There are a lot of other things to like about the DFI board, other than its tweaking and overclock potential. I like the layout. I like the fact that an XP-120 fits it. I like the CMOS reloaded. I like that fact that installing a SATA drive was easy and needed no driver disk. And, most of all, I like the active support community that exist out there, such as DFI street.