I'm currently using only the keyboard part of Microsoft's Wireless Optical Desktop Pro, since I wanted a wireless ergonomic-split keyboard, and this combo was the only way to get that combination of features (split keyboards are hard to find, and the few there are besides this one are wired). I am also using the Logitech MX1000 mouse. These work perfectly fine together, even with both receivers sitting right next to each other beside my monitor. I'm not sure if there would be issues using a keyboard and mouse of the same brand. All the wireless input devices I've seen have multiple channels, though, so you should be able to find a setting that works.