I have to say just this.
I was offered some great jobs at 20K more than what I make now, but I get tons more time off, comp time, completely paid benefits, and great retirement matching. Most of all, I love what I do and so I don't dread going in every day, and I can come home and enjoy my evenings and weekends. It's only been 2 years and my experience has gone above and beyond that of my coworkers at my previous position, plus working for a smaller company I have been given management and training opportunities I would not have had elsewhere. I would definately regret having taken the money over the enjoyment I have at my current position, plus the opportunities I have received that I would not have at my previous position.
If you are unhappy 8 hours a day 5 days a week, that is a large percentage of your life you spend unhappy, and you have the choice to change that! I would always suggest doing at work what makes you happy and excited, because you will come home and live life happier. It just depends on what you want and what makes you happy.