Yes, typically, all drives have 4 pin male recepticles on them which accept the wired female plugs from the PSU. SATA drives have a different recepticle and some PSU's have SATA connectors pre-installed, if not, an adapter is needed. Most of the newer high power PSU's will have more than enough 4 pin molex connectors (6, 8, or so)...Welcome to the forums!
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