If it was me (and unless the desk maker had already taken care of ventilation in some way - cool air intake at bottom front, warm air exhaust at upper rear), I'd be cutting out a big section of the floor of the PC compartment near the front (leaving enough wood to hold the PC) and lining it with metal mesh plus maybe a piece of foam AC filter material and cutting a hole or two in the back of the pedestal near the top for a fan(s). Definitely can't run a PC in an enclosed space if you want reliability and longevity out of it. All the fans in the world inside the PC itself won't save it - it would be just like running ducts from your exhaust fans right back into your intake fans.
I like that Cuzzi linked above too - but you can get similar at the big-box stores for less if you like the modern open-air style. But I take it you like (or require for image sake) the more formal style of furniture.
Also (unless the quality of their surface laminate has improved GREATLY recently) be very careful what you set directly on top of the laminated surfaces of that Bush/O'Sullivan type of furniture. Many types of rubbers will leech the plasticizers right out of it and make very ugly messes so protect the laminate surface with felt (or other dense cloth) or cork pads from any type of softer rubber or plastic materials (e.g. the non-slip feet on printers, scanners, other equipment, etc.). Another option is to put laminate over the Bush laminate like Formica or the GE equivalent that isn't so sensitive. Or cut a sheet of 1/4" furniture grade plywood and put a nice polyurethane/stain finish on it to cover the Bush laminate. OTOH, you could get REAL wood furniture to begin with and not have to worry about it. More money, of course... Like your mama taught you - never put anything in direct, long-term contact with "nice" wood surfaces: felt, cork, cloth only.
.bh.