No. The team speed and individual skills of an NFL team would very likely surpass that of even the best college team. I would be willing to bet that a team like this year's Sooners would put up a fight against say the Bengals or Lions, but ultimately, I think the NFL team would win. However, I think that a college all-star team (say the 1st and 2nd team All-Americans) would have a chance at winning against a bad NFL team if they were given the chance to practice together for a while.
-Tom