having to move a floor mounted tower that is hard wired into a network, connected to several external devices, i.e., scanner, laser printer, inkjet, label/stamp printer, external drives, USB hubs, and power boxes is not a simple task.
To this point... I totally agree. It always amazes me hearing people who have an everything-in-the-monitor mac and complain that they're so bulky because they have an external harddrive attached with that horribly ugly cable. One. One external harddrive. You know why I don't want to lift up my monitor, leave my apartment, find somewhere outdoors, put my desktop down gently, open it up, and blow air into it? Because I built this thing myself and have added to it over several years (with a lot of help from @mfenn actually :thumbsup

and it would mean unplugging two printers, a scanner, a monitor, ethernet, A/V output to TV, keyboard and mouse, a few USB peripherals that only play nice with certain USB ports, and speakers, and it's just damned impractical and my strict, albeit basic, ideology is the less it moves the less chance my desktop has of being in an accident. My wife is very allergic, we hate things being dusty around the house because we have furniture, records, books, devices that we like keeping in nice condition and every time we clean the desktop with canned air, one of us has to stand there with the vacuum at a distance to not cause static problems with the components. It's infuriating. Any DIY-er or home hardware aficionado will tell you that compressed air in any form is only useful in a shop that is built to allow for a mess or outdoors. Plus, there is no way that you aren't just dispersing the dust to other parts of the computer. Sure, it goes up in the air. And then when you put the computer back together and the fans start up again drawing in any air around it into the vortexes created by the fans, where do you think that dust goes?
My only problem with swiffer sheets is that they shred and their micro-threads get stuck on anything remotely pointy. Qtips work great, qtips made from swiffer fabric for cleaning devices would be even better. Don't know why they don't make any.
Now, what I really need, if anyone can help is to find out if there is anything mesh-like I can put on my grill openings that has holes small enough to stop debris from falling into the roof of my tower but large enough to breath ok. My cats have a tendency to walk over the tower because I have to keep it low and they're super clean, but of course their feet will always have some tiny amount of powdered dust between their toes from the wood-based litter we use. Any thoughts?