Okay, I've figured it out - mostly.
After setting it up the way you want, you go to profiles - profile manager. Tell it to save ALL CATALYST SETTINGS. You can go to Activation and set a shortcut too, if you want. They're nice and convenient.
This still leaves a problem. It may place them in the wrong order, depending what port they're plugged into.
Right-click the one that's on the wrong side and click swap. Swap it with the correct monitor, then SAVE ALL SETTINGS again. - For extended. Eyefinity is about the same. SAVE ALL after getting it the way you want.
Unfortunately, I can't make it save my 4th monitor correctly so I disabled it.