I am building a new rig and the memory is the only parts that I haven't purchased yet.. Here is what I have so far... 1. ASUS P8Z68 V/Pro (Z68 Mobo) 2. Sapphire 7850 (2gb memory) 3. Corsair 750TX PSU I want to have 16gb memory... I am a web developer and use Photoshop all day long. I am torn between (2x8) and (4x4) and price is not a contributing factor in my decision. So... I have been looking on Newegg and see that the 2x8 is a little more cost, but like I said, that doesn't matter... What does matter is that I see that if I go wit the 2x8 the CAS latency is 10 or 11 vs the 9 on the 4x4 sticks... So.. in the grand scheme of things, would I notice any performance difference between 4 sticks of CAS 9 vs 2 sticks (2x8) of CAS 10 or 11? I do plan to overclock a little but not much... I think I would rather go with the (2x8) choice, but not if the CAS of 10 or 11 is going to degrade my performance. Suggestions? Thank you so much!