I'm not familiar with MSI motherboards and BIOS's.
But I WILL tell you about a hair-raising, heart-stopping panic I went through last summer, and you'd best listen before proceeding.
Keep in mind, I've been flashing BIOS's on PCs since 1993. I can't COUNT the number of times I've done it; and I've done it several times each for a variety of machines. In those days, you had a "flash" program and a "bin" file containing the new BIOS -- which you prepared on a 3.5" floppy with DOS MsDos.sys and Command.com to boot from floppy. It was always a cinch.
I have ASUS motherboards now. There are three ways to flash the BIOS.
1) From a floppy similar to the method already described
2) Within the BIOS, there is a sub-menu item for a feature called "EZ_Flash." you still need the "bin" file on a floppy.
3) ASUS Update -- a Windows program
I only started testing the water with Asus Update a couple years ago, and several times, it worked just fine. But the prevailing wisdom on the street says "don't do it . . . don't . . . . do . . . . it!!"
Last summer, I forgot to clear the CMOS before flashing, and what's worse, by flashing from the Windows program. I could never get the system to boot; I tried every trick I know of. The symptoms pointed to a corrupted BIOS.
When that happens, and before arranging an RMA under warranty for your motherboard, go to
BIOS MAN .
$25 buys a year's subscription for subsequent flashes. They'll send you the correct PLCC BIOS chip for your machine, with the BIOS version you requested via your on-line order. They communicate very well by e-mail. Very nice.
Otherwise, ALWAYS clear the CMOS (with computer unplugged, turned off), and ALWAYS use the more primitive method for flashing.