Cannabis spray trial

BBond

Diamond Member
Oct 3, 2004
8,363
0
0
There are very few totally synthetic drugs. Most of the drugs we get off the shelf or from our pharmacist come from Earth's flora and fauna.

For example, aspirin came originally from the willow plant. Opiates come from Poppy seeds. One of the most potent anti-cancer drugs, Taxol comes from the Pacific Yew tree. Premarin comes from horse urine.

Why, in light of the known beneficial effects of plant and animal based compounds, does the pharmacalogical world ingore Cannabis? Because of a ridiculous scare campaign begun in the 1930s right here in the USA.

Well, the medical industry is beginnng to wake up and explore the benefits of the compounds found in Cannabis, and their findings are very promising. They are also finding ways to reduce the intoxicating side effects. But, due to arcane ideas exemplified in films such as "Reefer Madness" and ridiculous notions without basis the studies aren't being conducted in the USA, they're being done overseas in the UK.

We get to fall even further behind in medical science.

Read all about it.

Cannabis spray trial had dramatic results

A CANNABIS mouth spray tested on arthritis sufferers at Northampton General Hospital has shown dramatic pain relieving results.

The hospital's consultant rheumatologist Dr Meilien Ho carried out the trial on 15 patients at the hospital's rheumatology clinic as part of a ground-breaking study into the Class C drug's powers to tackle the debilitating condition.

And the results of the preliminary research reveal the drug eased pain and slowed down the disease for patients.

Dr Ho said: "It is very interesting and exciting research and the results have been very encouraging.

"There were a number of positive results showing the spray was beneficial."
The spray, called Sativex, was tested on patients at centres in Northampton, Bath and Birmingham.

Around 31 patients were given the drug for five weeks while another 27 in the trial were handed a dummy spray, with the subjects unsure if they were really taking the real drug.

The results of the study, which has taken over two years to complete, show the drug reduced pain, helped mobility for sufferers and slowed down development of the condition.

But the cannabis spray is not like the more common form of the drug.

Dr Ho explained: "This is quite different to the cannabis you get on the street.

"It's controlled so the patients don't get so much of a high.

"The cannabis people smoke is very variable but we have used the compounds of it that have the most medicinal benefit."

Now the doctors in charge of the research are calling for a larger study into the drug.
They hope to see it eventually used as an additional treatment for the condition, alongside the conventional anti-inflammatory drugs and disease-modifying medication.

"These investigations are very preliminary and show just a small change. But it is a start. There is a lot more work to do on this.

I'm positive it can help patients in the long run and am looking forward to hopefully investigating it further in the future," added Dr Ho.


Cannabis-based Drug Eases Arthritis Pain

November 9, 2005?

WEDNESDAY, Nov. 9 (HealthDay News) ? The first-ever study focused on a cannabis-based medicine aimed at easing the pain of rheumatoid arthritis (RA) finds it may help suppress the disease.

The results are "encouraging, with overall improvements in pain on movement and at rest, improvement in the quality of sleep and improvement in the overall condition of the patients' arthritis," researcher Dr. Ronald Jubb, a consultant rheumatologist at University Hospital Birmingham, in England, said in a prepared statement.

As reported online Wednesday in the journal Rheumatology, the small, five-week study included 31 RA patients who received the cannabis-based medicine Sativex and 27 RA patients who received a placebo. Patients in the study could self-administer Sativex ? an oral spray ? up to a maximum of six doses a day.

Side effects experienced by those on the cannabis-based medicine were mostly mild to moderate, including dizziness, light-headedness, dry mouth and nausea.

The researchers concluded that the findings of this small study warrant a larger trial to study in more detail the effects of cannabis-based therapies on RA.

 

Rainsford

Lifer
Apr 25, 2001
17,515
0
0
I don't understand why people are against medical pot, personally. It's a lot less harmful than most other legal drugs in wide use today, and it has been shown to help in a lot of situations where other drugs have proven effective. What's not to like about that?
 

azazyel

Diamond Member
Oct 6, 2000
5,872
1
81
Originally posted by: Rainsford
I don't understand why people are against medical pot, personally. It's a lot less harmful than most other legal drugs in wide use today, and it has been shown to help in a lot of situations where other drugs have proven effective. What's not to like about that?

Because you don't need a pharmaceutical company to produce it for you.
 

dahunan

Lifer
Jan 10, 2002
18,191
3
0
Originally posted by: azazyel
Originally posted by: Rainsford
I don't understand why people are against medical pot, personally. It's a lot less harmful than most other legal drugs in wide use today, and it has been shown to help in a lot of situations where other drugs have proven effective. What's not to like about that?

Because you don't need a pharmaceutical company to produce it for you.

;)$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$;)
 

cKGunslinger

Lifer
Nov 29, 1999
16,408
57
91
Originally posted by: azazyel
Originally posted by: Rainsford
I don't understand why people are against medical pot, personally. It's a lot less harmful than most other legal drugs in wide use today, and it has been shown to help in a lot of situations where other drugs have proven effective. What's not to like about that?
Because you don't need a pharmaceutical company to produce it for you.
Bingo!
 

azazyel

Diamond Member
Oct 6, 2000
5,872
1
81
Originally posted by: cKGunslinger
Originally posted by: azazyel
Originally posted by: Rainsford
I don't understand why people are against medical pot, personally. It's a lot less harmful than most other legal drugs in wide use today, and it has been shown to help in a lot of situations where other drugs have proven effective. What's not to like about that?
Because you don't need a pharmaceutical company to produce it for you.
Bingo!

Just another example of the government putting corporations above the welfare of the people.
 

dahunan

Lifer
Jan 10, 2002
18,191
3
0
Originally posted by: azazyel
Originally posted by: cKGunslinger
Originally posted by: azazyel
Originally posted by: Rainsford
I don't understand why people are against medical pot, personally. It's a lot less harmful than most other legal drugs in wide use today, and it has been shown to help in a lot of situations where other drugs have proven effective. What's not to like about that?
Because you don't need a pharmaceutical company to produce it for you.
Bingo!

Just another example of the government putting corporations above the welfare of the people.

They give the Bog Corps Tax Cuts and then Cut Govt Programs for the PEOPLE.. .Who IS the Govt?

shall have a new birth of freedom -- and that government of the corporations, by the corporations, for the corporations, shall not perish from the earth
 

azazyel

Diamond Member
Oct 6, 2000
5,872
1
81
Originally posted by: dahunan
Originally posted by: azazyel

Just another example of the government putting corporations above the welfare of the people.

They give the Bog Corps Tax Cuts and then Cut Govt Programs for the PEOPLE.. .Who IS the Govt?

shall have a new birth of freedom -- and that government of the corporations, by the corporations, for the corporations, shall not perish from the earth

And that you are completely free....to do what we tell you.
 

ShadesOfGrey

Golden Member
Jun 28, 2005
1,523
0
0
I'm not sure how someone could be against something like this. Sure, control it or whatever you need to do but if it works, why stand in the way?
 

Rainsford

Lifer
Apr 25, 2001
17,515
0
0
Originally posted by: azazyel
Originally posted by: Rainsford
I don't understand why people are against medical pot, personally. It's a lot less harmful than most other legal drugs in wide use today, and it has been shown to help in a lot of situations where other drugs have proven effective. What's not to like about that?

Because you don't need a pharmaceutical company to produce it for you.

Ah, true. But that just explains the tools in government. There are a fair number of regular people who think the concept of medical weed is like letting the terrorists win. Are they just idiots who don't know when they are being lied to?
 

BBond

Diamond Member
Oct 3, 2004
8,363
0
0
Although Cannabis can be easily grown, this particular study examned a spray that is made up of compounds found in Cannabis -- without the intoxicating effects. I can't understand how anyone could possibly oppose this.

To do so would be akin to opposing every drug made from plants.

The idea is to isolate the beneficial compounds and reduce side effects -- aka, the "high".

 

azazyel

Diamond Member
Oct 6, 2000
5,872
1
81
Originally posted by: BBond
Although Cannabis can be easily grown, this particular study examned a spray that is made up of compounds found in Cannabis -- without the intoxicating effects. I can't understand how anyone could possibly oppose this.

To do so would be akin to opposing every drug made from plants.

The idea is to isolate the beneficial compounds and reduce side effects -- aka, the "high".

buzz kill and anyways, the old people shouldn't be deprived of the buzz.
 

maluckey

Platinum Member
Jan 31, 2003
2,933
0
71
No final clinical trials, and no major publications have tested the product as of yet. So far it's only use is with advanced MS patients. The main side effects are fatigue dzziness and nausea. As far as it's use outside of MS patients, there is likely to be no testing. It is only approved for use with Neuropathic pain, as it's overall pain relief properties are not as effective as other currently available drugs.

As far as the drug company argument. Hogwash. Bayer already is in the mix with the drug, called Salivex. As far as growing your own........nobody grows their own tobacco, and it's easier to grow than cannabis, and the active ingredients in Marijuana are already available in Marinol...here in the United States. It is not any more effective than other currently available drugs. That's why Marijuana is still a scehedule I drug.
 

BBond

Diamond Member
Oct 3, 2004
8,363
0
0
Originally posted by: maluckey
No final clinical trials, and no major publications have tested the product as of yet. So far it's only use is with advanced MS patients. The main side effects are fatigue dzziness and nausea. As far as it's use outside of MS patients, there is likely to be no testing. It is only approved for use with Neuropathic pain, as it's overall pain relief properties are not as effective as other currently available drugs.

As far as the drug company argument. Hogwash. Bayer already is in the mix with the drug, called Salivex. As far as growing your own........nobody grows their own tobacco, and it's easier to grow than cannabis, and the active ingredients in Marijuana are already available in Marinol...here in the United States. It is not any more effective than other currently available drugs. That's why Marijuana is still a scehedule I drug.

Even if it isn't any more effective than other pain relievers, the pain relievers that are on a par with Cannabis are all addictive -- and I'm not talking about psychological addiction. They are physically addicting -- serious physical withdrawal symptoms.

Why not use pain relievers that are as effective as opiates but without the serious side effect of physical addiction?

MJ is a schedule I drug because of fairy tales. The truly dangerous opiates are controlled for medical use. Refusing to do the same with MJ, a drug that you admit is as effective, is just stupid, IMO.


 

azazyel

Diamond Member
Oct 6, 2000
5,872
1
81
Originally posted by: maluckey
No final clinical trials, and no major publications have tested the product as of yet. So far it's only use is with advanced MS patients. The main side effects are fatigue dzziness and nausea. As far as it's use outside of MS patients, there is likely to be no testing. It is only approved for use with Neuropathic pain, as it's overall pain relief properties are not as effective as other currently available drugs.

As far as the drug company argument. Hogwash. Bayer already is in the mix with the drug, called Salivex. As far as growing your own........nobody grows their own tobacco, and it's easier to grow than cannabis, and the active ingredients in Marijuana are already available in Marinol...here in the United States. It is not any more effective than other currently available drugs. That's why Marijuana is still a scehedule I drug.

You have no idea what you are spouting.

Have you tried Marinol? That sh!t will knock you on your arse! It's like eating a pan of brownies.

Hard to grow, are you friggen joking me. If a professional stoner can grow a crop anyone can.

 

maluckey

Platinum Member
Jan 31, 2003
2,933
0
71
azazyel

I do indeed know what I'm talking about. The wuestion is do you? Marinol comes in varying dosages....but you didn't know that of course. This drug would not legalize MJ, japparently just the active ingredient (which is already in use BTW). The only difference is that it can now be used as a spray instead of as a pill.

Also, Cannabis is more difficult to grow than tobacco, and nobody does that (grows tobacco) for themselves because they are lazy and can buy tobacco.

BBond,

You are missing my argument.

No final trials, no long term studdies or publications in any respectable journal etc. Also I did not say that the drug was just as effective...you did. I said
It is not any more effective than other currently available drugs
. It's a vague way of saying that it's not better.

If it's not better, and it is only supposedly effective for neuropathy, and the side effects are not fully tested. Why make such a fuss?

The MJ debate is still ongoing, and to date, there has not been one MJ clinical trial that has stood scrutiny by the medical community, where MJ has been the preferred/superior drug.