With standard computer use (switching from keyboards, to mouse, to other office equipment), study after study has shown that there is NO chance of getting carpel tunnel syndrome from the keyboard/mouse.
However, if you don't use it in the standard way (say you game for hours on end with just the mouse), I suspect there is a slight but noticible risk for carpel tunnel.
Just switch things up a bit. Don't use anything repetitively without breaks. And change your angles during the usage if you have to use anything for long periods.