I've ordered Ibuprofen and other OTC drugs over the internet before and they came via USPS, UPS, and Fed Ex. None had any problems. I think the key here is to make sure that the drugs being sent are legal. Also, make sure the party to recieve them is supposed to have them, or is the owner of them. There shouldn't be too many other problems beyond that, but you still want to check if you use the USPS to send them. It would be pretty bad to get 'caught' sending something like that if it were against their rule....that is, IF they do any package screening.