Depends on what kind of OEM key. Since we're talking about a Dell, I'm assuming it has a SLIC key embedded in the BIOS. In which case 10 should register and activate automatically.
Since I'm not in the US, I don't know the view on system builder keys.
If you are upgrading, you won't need a key at all. Just did my neighbors last weekend. I updated his current install, and it activated just fine, and gave him a digital license. Then I pulled out the HD and put in an SSD for a clean install. No key was ever needed. If you do the clean install after updating, just choose "I don't have a product key" when it asks.