If I build a new rig, then most likely; right now all my computers are AXP-era, so nothing's going to carry over - that is, except for my P-M laptop, which obviously doesn't affect anything. Bottom line: if they prove to be good OCers with decent, inexpensive motherboards available, why not? DDR2 uses less power and has better latency and bandwidth per the AT review, so why not? Then again, "Conroe" is coming, so I'll likely keep waiting.