Brands are pretty much the same for hard drives, but your data is precious and you should get the most reliable drive out there. Opinions will vary from user to user, with some going with Western Digital (for faster drives), Seagate (for quieter drives), and Maxtor and IBM being some other brands. RAM is also important, and again, the better brand will probably help your system last longer. Popular RAM manufacturers are Crucial, Kingston, and Mushkin to name a few. Hope this helps.