Well, I'm considering it since I recently got a new Zen Vision M. The HDD in my old Dell was a 5GB Seagate ST-1, which has the CF form factor. I've tried booting from USB in the past, and this is pretty much the same thing (if your card reader is USB)...it's better than booting from LiveCD because you can make changes and save files easily without losing them on the next boot up.