First, make sure all cables and connections involved in the harddisk subsystem are secure.
Second, make sure all jumper settings related to this subsystem are also properly selected.
Third, make sure your drive is showing up in the BIOS. If not, try manually enetering in the information necessary (Heads, Cylinders, Etc.). The information is usually on a label on the harddisk.
Fourth, Make sure your drive is properly partitioned. If not, you will need to do this before you can format it.