I bought a ThermalTake V4 Black Edition at Microcenter last time I was there, and it seemed like the cheapest non-crappy case that they had.
It's not a bad case, it's fairly nice, but the Antec 300 is much, much nicer. The Antec 300 is also more solidly built, has two intake fan slots, removable dust filter on the inside of the bezel, and the Antec comes with both the rear exhaust and the top exhaust fans. The V4 only comes with one LED rear exhaust fan, and on mine, it sometimes doesn't even spin up when I power the computer on. That should be an example of ThermalTake's less than stellar quality. The Antec fans appear to be tri-cool fans, but not lighted. (Antec 300 Illusion, I think that they are blue LED fans).
-My TT fan was fine (using it for side intake on my GTX 460). It's very quiet because it spins at <1000 RPM.
Also, the middle post where you would normally put a standoff, on the V4 (and V3), there is a bolt coming up there instead. A non-removable bolt, and with no nut or anything included to screw down on it. I don't know why they went with that design, but I'm guessing, that allows you to lay the mobo down, and align it, and with the bolt sticking up, it allows you to screw in the other screws without worrying about keeping the mobo aligned.
-It's there for exactly that reason. To help you align the motherboard during installation.
Also, the V4 doesn't use standoffs, it has pre-formed and pre-drilled standoffs. That shows that it is a "cheap" case, as only the cheapest cases don't even bother to include proper brass standoffs. It does make assembly quicker, but I prefer the normal standoffs, of which the Antec 300 uses.
-What's wrong with pre-drilled standoffs? They are no less sturdy than normal brass standoffs and make installation faster since you don't have to position the standoffs and screw them in.
Oh, and it seems that ThermalTake includes only a few of the tool-less HD/CD mounts in the V4. You have to step up to the Dokker to get the full compliment of them.
-Mine came with 2 tool-less mounts for the 5.25" bays and 4 for the 3.5" bays. Plenty IMO. The Antec 300 has no tool-less bays to speak of.