Important question.
Do you have DVD, CD, CD-R or other drives in the system.
The channels only run as fast as the slowest interface on the channel, so you have to be careful. If the original HD is an ATA 33 driuve and hte new one is a ATA 66, for example, the ATA 66 will actually run as if it were an ATA 33. Also, older CD-ROMs arn't even ATA 33, so you have to be careful with them.
So, I guess I/we neeed to know more about your drives/CD-ROMs, etc and what channel(s) they are on. If possible, tell us if they are ATA 33/66/100, or if you don't know.
Hope this helps,
Karl