The fans on the Twin Frozr II are pretty small, though. 80mm and very thin as well. Whereas I think a lot of single fan coolers are 92mm (pretty sure the Cyclone is at least, not as sure about DirectCU) and thicker as well, so it won't need to spin as fast to push the same amount of air.
But truthfully I don't think you can go wrong with either, both seem to be great coolers. I'd probably pick the Twin Frozr II because I think it looks better, but that's just me. 😛