Looks like I spoke too soon.
With all the work I've done, gaming works fine with AGP 4X and Fast Writes,
however, I'm getting occasional lockups using 2D applications, such as IE and Windows Media Player (go figure).
For now, as kludgy as it is, if I'm doing anything important in 2D, I'll set the System Performance to Normal, when gaming, I'll have to reboot with it set to Optimal.
I may consider updating to the most recent BIOS revision later tonight as well, just to see if that has any effect. Failing that, I suppose it's just a situation where I'll need to sit on my hands and hope the next VIA 4-in-1 drivers solve any remaining issues.