Their is an ATX standard that I believe actually is a standard for the motherboard, the PS and the case. Most all new mobos & PS's are ATX. The standard insures that everything will physically fit together. The earlier AT standard is not forward compatible with ATX.
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From whatis.com:
ATX is an industry-wide open specification for a desktop computer's motherboard. The most current version (December, 1996) is Specification 2.0.
ATX improves the motherboard design by taking the small AT motherboard that has been an industry standard and rotating by 90 degrees the layout of the microprocessor and expansion slots. This allows space for more full-length add-in cards. A double-height aperture is specified for the rear of the chassis, allowing more possible I/O arrangements for a variety of devices such as TV input and output, LAN connection, and so forth. The new layout is also intended to be less costly to manufacture. Fewer cables will be needed. The power supply has a side-mounted fan, allowing direct cooling of the processor and cards, making a secondary fan unnecessary. Version 2.0 incorporates improvements suggested by chassis and power supply vendors.
Almost all major computer manufacturers, including IBM, Compaq, and Apple are building desktops with ATX motherboards. IBM is using ATX in both Intel and PowerPC platforms.