Yeah, for "mission critical" applications you don't overclock and you use ECC memory.You get a server board and ecc ram. 🙂
hp sells 4GB SLC SDHC and 2GB USB SLC SDHC for vmware. its rebadged but SLC goes along way further than cheap mlc.
I don't see any difference in speed between 2GB sticks and 4 GB sticks.