I had one for a while. I don't know if panel consistency is an issue because unlike Ravynmagi I had no problems with the display being washed out. It is low resolution (comparatively; 1280 x 800), but that's fairly standard for Windows tablets at the low end. I'd expect more if it were a more expensive tablet or if it geared toward media consumption tablet like the Nexus 7 HD, but it's good for what it is. I had no issues with the body or construction, either, it's pretty much in line with all of ASUS' other tablets. The Surface RTs and Pros are much better in construction and material quality, of course.
Ravynmagi is spot on about the fingerprints, though: it does accumulate fingerprints (expect to wipe the screen frequently if you use touch more than the stylus), but you get used to it, and it's worth it for the excellent digitizer. Makes OneNote a pleasure to use, and it's suitable for drawing. I'm not an artist really, though, but did have a good experience using apps like FreshPaint and desktop Paint.NET. The digitizer and GPS easily make it worth the price tag versus all the other $200 - $300 Windows 8.1 tablets.
I sold mine on Swappa, but only because I somehow got a scratch on mine and the pen was getting caught in it a bit. Not a major problem - and I think ASUS includes it in the warranty - but I want to get a Surface Pro soon for the faster hardware, anyway, and since I don't currently have a laptop.
If your sister uses Photoshop or Illustrator, or any other heavy-duty desktop apps, she'll want a Pro. The Atom-based tablets are okay for old or lightweight desktop programs or Windows 8 apps, but they will feel slow for anything more powerful. And if she's a professional artist or plans on becoming one, the display on the Pros is much more accurate and higher resolution. Plus there's more room to work with - an 8" tablet is good for note taking and casual drawing, but larger tablets are preferable so you don't have to zoom a lot for detail.