Originally posted by: aphex
Well I actually live about 45 mins south in Sarasota, but i've stayed in Tampa hotels twice in the 4-5 years we've lived in this coast.
My favorite hotel downtown is the Marriott Waterside Hotel & Marina. Can be a bit pricey, but IMO its worth the added cost due to its prime location at the southern part of downtown and quick access to Ybor, Channelside, downtown, etc.... Its a beautiful hotel with extremely comfy beds and just a great location. Its about a 4-5 minute drive to Ybor, 1-2 minute drive to Channelside, and literally across the street from the St. Pete Times Forum and the rest of downtown.
The new Embassy Suites across the street from it is nice as well (and cheaper by a little as well), it opened just a few months ago. There is also a decent Westin Tampa Harbor Island hotel, but the reviews are mixed at tripadvisor (i've never stayed there myself).
I would stay away from most hotels over by the airport (except the Quorum or the Airport Marriott), all of the hotels in south tampa (dale mabry area, south of kennedy), and anything north of I-275 as many of them are older and with traffic, can be a bit of a distance to get anywhere (especially up by Busch Gardens). The only "bad" part of downtown to avoid is the eastern part of the downtown area, just below and above I-275 and just before you hit YBor. The 'projects' are an appropriate name
If you want to save some money (upwards of $50-$100 less a night), consider staying in a hotel in Brandon and taking the Crosstown Expressway into Ybor and Tampa. Its about a 10 minute drive east of Tampa, not much going around there other than a nice mall and tons of stores (Brandon Town Center and surrounding area) and tons of Tampa commuters, but its a quick shot right into Tampa and you can save a decent amount by staying around the area. The corner of 60 and I-75 has a slew of hotels that get excellent reviews (specifically the Homewood Suites)
Personally though, I would stay in the Marriott Waterside if you can swing it, I really just love that hotel...
BTW - Welcome to the area!