Amphetamines Have Bigger Impact on Male Brain WEDNESDAY, April 12

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Jul 16, 2001
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WEDNESDAY, April 12 (HealthDay News) -- Amphetamines appear to have a greater effect on male brains than female brains, a new study suggests.

"These appear to be the first clinical studies whose results may help explain why we see a greater number of men abusing amphetamines than women," study leader Dr. Gary S. Wand, professor of endocrinology at Johns Hopkins School of Medicine, Baltimore, said in a prepared statement.







The finding could also help in the development of tailored treatments for drug abuse and neurological diseases, the researchers said.

Wand's team used PET scans to observe the brains of 28 men and 15 women, ages 18 to 29. The study found evidence that, compared to women, men's brains released up to three times the amount of the neurotransmitter chemical dopamine when exposed to amphetamines.