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After drinking.. Which is the one that is so bad for you...

I thought it was "all of the above" since any medicine is going to tax your liver over and above the alcohol.
 
I have violent allergic reactions to salicylicates (asprin, advil, ibuprofen etc...) so the only thing I ever take it Tylenol.... I didn't know it was bad to take with alcohol.... :Q
 
Gosh. None of that stuff. For heavy sessions, several isotonic drinks right before bed to help rehydrate and Alka Seltzer the next morning if needed. Otherwise good ol' water should suffice.
 
Originally posted by: Mucho
Tylenol and Alcohol are a bad mix it can cause liver damage

You mean "MORE" liver damage.

" just drink lots of water, its not worth the risk."

pffft Somebody who cares so little about their own health that they would get so drunk as to get a hangover should worry about the risk of which pain reliever is dangerous? News flash, you got bigger problems than that.
 
Originally posted by: ahurtt

pffft Somebody who cares so little about their own health that they would get so drunk as to get a hangover should worry about the risk of which pain reliever is dangerous? News flash, you got bigger problems than that.


Meh. Anyone who's so uptight that they feel compelled to write such pointless, censorious commentary about other people's relatively harmless conduct on a public BBS has a whole different set of problems.

In answer to the original post, you're referring to acetominophen (aka Tylenol). My understanding is that the size of a theraputic dose is surprisingly close to a toxic dose, and the blood thinning that occurs through drinking just aggravates this. Tylenol is by far the most common cause of toxic drug overdoses, and can cause liver failure and severe damage. The short answer is, stay away from combining Tylenol with alcohol.
 
If you took a couple of Tylenol's last night after drinking a bit, it's not the end of the world, but really try not to do it anymore. I've seen guys take down many vicodins then drink 6-12 beers in a night. Ouch! :Q Basically, your liver is working very hard on getting rid of the alcohol and adding tylenol to the mix makes it overloaded, possibly causing damage. That and it can make your stomach hurt so bad it feels like its being tore apart by the tylenol. My stupid-ass took a handful of Darvocets (yuck, I know) once then went to a party, drank a bunch of beers, and I was holding my stomach by the end of the night.
 
all of the above. pick your poison. when combined with alcohol, advil (ibuprofen) and aleve (naproxen sodium) can cause stomach bleeding, and tylenol (acetomeniphine) can cause liver damage.
 
It's tylenol I think, and if you're drinking enough that you have to take thme before bed (I used to do that when I was a dumb sh*t), then drink less. This is your liver that you have to live with forever. Stop drinking so damn much. Suck down a ton of gatorade, and then have some pills the next morning after the alcohol has been processed, to deal with the hangover. As mentioned, all are bad with booze.
 
Just drink more in the morning. Some alcohol first and then a bunch of water. It'll be really hard but you'll feel better.
 
i drink a large glass of water and take a vitamin B, it really does work. apparently alcohol destroys B, which is vital to your red blood cells. take a supplement really does help. google it, theres stuff out there. i used to think it was crap untill i started doing it.
 
Holy crap!

I never knew this stuff. My wife is a pharmacist and she never told me.

I used to always take tylenol after drinking but now I'll stop.

Thanks ATOT for extending my life. 😉
 
Acetominophen (sp) attacks the liver. Aspirin attacks the stomach. So, Tylenol being the former is not great after a heavy night of drinking, or if you already have liver troubles.
 
Everyone's right - it is acetominophen (Tylenol) thats so bad for your liver. Its causes diffuse necrosis because of the generation of excessive reactive oxygen.

But here's a little known fact: the reason alcohol and Tylenol don't mix is because alcohol causes a specific protein to be made in your liver cells. This protein is responsible for metabolizing chemicals, and can (and will) also act on tylenol when it enters the liver. The problem is that this protein acts in a funky way with Tylenol, metabolizing it incompletely and leaving it free to create radicals and other damaging things.

The thing is, you need to have the protein already present in order to cause liver damage after taking Tylenol. Thats why you shouldn't take Tylenol after drinking all night. But there's no reason you can't pop a Tyelonol if you have a headache BEFORE you start drinking (like a couple hours or so). It takes about an hour or two for the protein to be made after drinking, by which time the Tylenol will have been metabolized and you won't be at risk for liver damage. And you won't have a headache.

Disclaimer: this doesn't apply to you if you drink alot (the bottle says 3 drink A DAY or more), because you've always got this protein hanging around...

 
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