It will work on an Opteron, as Opteron and Athlon64 have the same retention mechanism. ECC means error correcting code, which is generally reserved for servers and high end workstations.
ECC doesn't mean registered. Most ECC RAM is registered anyways, so don't get hung up on it. It's probably better to Google your little quandry and save yourself the time and agony of figuring out which one of us is right .
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