A lot of games Max Payne and Diablo II for instance have what's called safedisc2 copyright protection they need to check the CD its self, in fact most burners don't copy that protection, clonecd or not, so you could copy the entire contents of a CD to a partition and I don't think it would matter, I am not sure if there is a way to have the game look at a partition on your hard drive instead of your CD-rom drive. as far as ghost goes it copies the files in a ,gho format so I don't think that's a viable option. Now I have only used ghost to back up entire partitions and I always use it to compress the files, and I always use it in dos. And remember if you start adding partitions to your hard drive that the letters to your cd-rom drives will change and that can screw things up.