Venice is definiltey the way to go. First of all, it's cheaper because of supply + demand. Nobody wants the old Winchesters anymore, they all want the new Rev E Venices. The Venice has an improved memory controller which will allow you to run 4 sticks of DDR400 @ 400mhz, instead of the old memory controller which downlocked them all to 333mhz. Rev E A64's also have SSE3 instruction. They overclock better too.