lol.. make the text bigger?
kinda defeats the purpose of getting a high resolution monitor
When you run at a higher DPI, you get much better fidelity in font rendering, which leads to less overall eyestrain. Additionally, and unlike simply running at a lower resolution, non-text elements of your experience can still render at full detail.
So if you're image editing for example, you can retain a usable size on your toolbars and panels, but you will see more of the image you're working with at a given zoom level. Or conversely, you can increase the zoom level and see the same amount of the image.
Basically, more resolution gives you more flexibility. (Though Windows still kind of sucks at high DPI compared to Mac and Linux.)