I have the PATA 16mb 250g Maxtor. Compared to the other 8mb Maxtors I have (as well my Seagates and WD's), the speed difference is noticable without having to use synthetic benchmark utilities to check. Particularly in applications loading up and in defragging. I'd say it's the fastest drive I've used to date.
The only thing I don't like about it is that it runs hotter than any other HDD I own. It's the first HDD I've owned that prompted me to get a HDD cooler. Not that there was a problem without it, it was just for the piece of mind.