Got From Dust at release over the summer, every now and then I pick it up and I'm slowly finishing it. The music and ambience is excellent, and the puzzle aspect of it really ramps up in the later levels, it gets genuinely hectic at times trying to manage your villages and god powers to keep them safe. The levels do get kind of long as well, which I think is the reason I still haven't beaten it, whenever I complete a level I usually feel more like taking a break than taking on the next challenge.
I think players who enjoy puzzles or RTS will find something in it. For the puzzler you can just find the quickest way through it, or the 'uber micro' RTS player can spend a long time creating a 'perfect' path or trying to cover the entire map with vegetation, drain all the lakes, build something out of lava. Even just as a toy it's very cool, seeing how you can shift and shape the landscape.
Keyboard and mouse control works fine, better even than a controller I'd wager, I wouldn't call it a shitty port by any means; just a normal port. It looks and plays like the original game, I don't see the problem. But you will need an Ubisoft login for whenever you run the game, and I have had it crash on me rarely.
Money well spent on my part at least.