$1,000-a-day miracle drug shocks U.S. health care system

techs

Lifer
Sep 26, 2000
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http://www.cbsnews.com/news/1000-a-day-miracle-drug-shocks-us-health-care-system/

$1,000-a-day miracle drug shocks U.S. health care system

Sovaldi, a new hepatitis C treatment, can cure up to 90 percent of patients within three months. There's just one problem: The drug costs $1,000 a day. That price tag has thrown the biotechnology world into turmoil, as lawmakers and insurance companies complain that Sovaldi's maker is trying to milk desperate patients.

Doctors are understandably finding it hard to pass over a drug that is so effective. As a result, Sovaldi's manufacturer, Gilead Sciences (GILD), is raking in the dough, while its shares have soared 53 percent over the last year. Sovaldi, in fact, may generate the biggest sales ever for a drug's first year. It could bring in a jaw-dropping $7 billion to $10 billion in sales this year alone, analysts say.

There are many sides to the Sovaldi story, and here's how the little pill affects them all:

Patients: There is no vaccine for hepatitis C, and some 3 million Americans are thought to have the virus. Many of them may have been infected through intravenous drug use. Before Sovaldi, patients had to deal with treatments like the injected interferon, which causes such severe flu-like symptoms that many chose to avoid it altogether.

Insurers: Companies being asked to foot the bill for Sovaldi are panicking. One of the hardest hit, Molina Healthcare (MOH), could see earnings drop by 18 percent because of Sovaldi, The Wall Street Journal reports. The head of Molina, Mario Molina, says that if everyone in the U.S. that had hepatitis C were treated with Sovaldi at list price, the tab would run to $227 billion, according to Forbes. To put that in perspective, the amount spent on all drugs in the U.S. is about $260 billion.

Doctors: Physicians are getting pressured to ease up on Sovaldi, but it's hard to pass over the drug when it works so well and has few side effects. Why allow someone to suffer when a cure is three months away?

Gilead: Sovaldi's maker says that even with its high price tag, Sovaldi is cheaper because it cures patients quickly and eliminates a long and expensive treatment using other drugs. Hepatitis C can eventually lead to cirrhosis of the liver and liver cancer.

Taxpayers: More than half of those with hepatitis C are veterans, prisoners, uninsured or on Medicaid, the New York Times reports. That requires taxpayers to pick up the bill.

Lawmakers: Perhaps motivated by the high costs to taxpayers, lawmakers are pushing Gilead to explain why it charges so much. It doesn't help that Gilead is offering Sovaldi in Egypt at a 99 percent discount to U.S. prices, or about $900 for a full course of treatment.

Gilead wants to tier its pricing based on a country's per-capita income. So patients in the U.K would pay about $57,000, Reuters reports, while Germans would pay $66,000 and Americans are paying $84,000.

For now, Gilead has a pretty tight lock on the market, but competitors such as AbbVie (ABBV) are expected to debut treatments later this year. But Congress has no power over individual drug costs, so it's unlikely that all the carping will lead to anything, writes Nathan Sadeghi-Nejad in Forbes. There are plenty of ironies here, not the least of which is that medical innovation is revealing the shortcomings of our health care system.

"The drug is a microcosm of the U.S. healthcare system's structural problems," Sadeghi-Nejad adds. "We want big scientific advances, but are not prepared to handle the costs of a drug so effective and tolerable that every patient wants it at once."



Wow. A grand a day, but it actually saves money. Too bad I didn't buy stock in the company
 

Blackjack200

Lifer
May 28, 2007
15,995
1,686
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It doesn't help that Gilead is offering Sovaldi in Egypt at a 99 percent discount to U.S. prices, or about $900 for a full course of treatment.

Gilead wants to tier its pricing based on a country's per-capita income. So patients in the U.K would pay about $57,000, Reuters reports, while Germans would pay $66,000 and Americans are paying $84,000.

So our per-capita income is 100 times more than Egypt's?
 
Mar 16, 2005
13,856
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Fuck pharma.

They probably already have cures for all major diseases and just waiting to profit.
 

halik

Lifer
Oct 10, 2000
25,696
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Wait 15 years and it will be free. IIRC they priced it relative to the total cost of treatment for people with hep C.
 

darkewaffle

Diamond Member
Oct 7, 2005
8,152
1
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Lawmakers: Perhaps motivated by the high costs to taxpayers, lawmakers are pushing Gilead to explain why it charges so much. It doesn't help that Gilead is offering Sovaldi in Egypt at a 99 percent discount to U.S. prices, or about $900 for a full course of treatment.

That's a bit suspect, but otherwise for better or worse it's their right to charge whatever they want.
 

ThatsABigOne

Diamond Member
Nov 8, 2010
4,422
23
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A cure for hep C, that's pretty amazing.

It is, and I am glad that I am one of the cured. :) No, I did not use Sovaldi. A load of antibiotics were taken when I was fighting against kidney cancer and after-effects of blood transfusion.
 

jaedaliu

Platinum Member
Feb 25, 2005
2,670
1
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Wait 15 years and it will be free. IIRC they priced it relative to the total cost of treatment for people with hep C.

Need to cover development cost, and need to make a profit so that they can fund research on future drugs that can turn a profit after the patent expires.

Vertex Pharmaceuticals has a cystic fibrosis drug that costs over $300k/year.

Pfizer's patent on Lipitor expired in 2011, and they have nothing to replace the income of the best selling drug in history.

And 20 years, not 15, but close enough.
 

Jimzz

Diamond Member
Oct 23, 2012
4,399
190
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Just wait for India to start making it and buy it online for a lot less.

If you price it high enough there are countries that will make it no matter the law in your country.
 

MarkXIX

Platinum Member
Jan 3, 2010
2,642
1
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The article isn't clear on what a "full course of treatment" is. $1000/day sounds ridiculous, but is that 10 doses in 10 days? 100 doses in 100 days?

It can be somewhat inferred from the Egyptian price of $900 which is 99% off the U.S. price, but it's still not clear.
 

jpeyton

Moderator in SFF, Notebooks, Pre-Built/Barebones
Moderator
Aug 23, 2003
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It doesn't help that Gilead is offering Sovaldi in Egypt at a 99 percent discount to U.S. prices, or about $900 for a full course of treatment.
So instead of paying $84,000 for treatment here, buy a ticket to Egypt ($1500), stay for 3 months in a nice apartment ($3000), and get fully treated ($900). Pocket the $78,600 difference and enjoy your vacation.
 

Scarpozzi

Lifer
Jun 13, 2000
26,389
1,778
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I know someone that could have used this. They ended up going the other route last month and got a liver transplant. All went pretty smooth except for a few bile duct leaks. I'm not sure what it cost them, but it was actually probably cheaper than that drug since they have insurance.
 

silverpig

Lifer
Jul 29, 2001
27,703
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what makes it cost 1000$ a day?

Pricing 101: There are 3 ways to price something (but really only 1 way).

1. Cost+ - take what it costs you to make it, add a profit margin (~50%) and that's your price
2. Comparables - price it the same as what your competitor is pricing the same thing at
3. Willingness to pay - price it below what the customer would pay to solve the problem your product solves in another way

#3 is the real way to price things, and that's probably how this drug is priced. Basically, they calculated that it'd cost >$84k to treat an American with HepC on average, so you charge $84k for it. It's a lot, but it's cheaper than the alternative.

Now, just what exactly they included in that cost is a matter for an expert pricing team. It would undoubtedly include the cost of alternative treatments, but may also include lost wages, etc. The government saves money on healthcare, and gains productive workers and their tax dollars.

The stuff might only cost $0.10 / pill to make, if you neglect all the sunk research costs, and the costs of all the drugs that didn't work.
 

Sluggo

Lifer
Jun 12, 2000
15,488
5
81

silverpig

Lifer
Jul 29, 2001
27,703
12
81
The article isn't clear on what a "full course of treatment" is. $1000/day sounds ridiculous, but is that 10 doses in 10 days? 100 doses in 100 days?

It can be somewhat inferred from the Egyptian price of $900 which is 99% off the U.S. price, but it's still not clear.

The article said it cures 90% of people within 3 months, and costs $84k USD.

So... ~$1000/day for ~90 days
 

techs

Lifer
Sep 26, 2000
28,559
4
0
It is, and I am glad that I am one of the cured. :) No, I did not use Sovaldi. A load of antibiotics were taken when I was fighting against kidney cancer and after-effects of blood transfusion.

I also have kidney cancer. I hope you are doing well. I sent you a pm.
 

JManInPhoenix

Golden Member
Sep 25, 2013
1,500
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I suspect the reason the price is so high, in addition to profit, is to cover the cost of future class action lawsuits for damages done by drug. ie, seems like the evening news is half drug commercials and half lawyer commercials to sue drug companies for drugs that came out a few years ago ... :p
 

Hayabusa Rider

Admin Emeritus & Elite Member
Jan 26, 2000
50,879
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The stuff might only cost $0.10 / pill to make

People tend to stop right there. What people fail to consider is what it costs to deliver the first pill.

I don't know the particulars, so we'll do a hypothetical. If it the total costs to bring a drug to market is a billion dollars you obviously have to recoup that money no matter how many use it. Then there's the ongoing costs of manufacture and regulatory compliance which is not trivial for a drug such as this.

Now we're talking real money, not 10 cents which is what would be fixated on. To be sure someone is going to be making $$$$ because they can, however the idea that this stuff is basically free is stupid.

What's funny is that the so called left leaning members complain about how the rich own so much of the worlds wealth, but when it comes to it the ARE the rich. Now a company is pricing in a way that accounts for that discrepancy and they are having cows over it. Gore anyone's ox but mine?