It is good you asked this question. First off most of the newer boards will work with 5000 series AM2 processors but the 4000 series have issues with AM2/AM2+/AM3 boards I found this out. My Asus M4A was fried 2x by the AMD AM2 Athlon X2 4000 series processor first time was 4200 and 4600 2nd...
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