The X-E1 and X-Pro1 both suffer from the same problem that the X100 had initially: slow focus.
Since then, they've all had firmware updates that somewhat remedied the issues, but...
If it were my first camera, I'd grab the X100S over any of the other Fuji X cameras right now.
The sensor is newer (much better noise performance at higher ISO and higher resolution), performance is faster than any of the other cameras for sure (thanks to hybrid phase detection and contrast detection AF system), optical viewfinder (love this on my X100), compact size, and best of all, fixed lens so no worries about dust in sensor, or about which lens to use. Just point and shoot.
Since I have a X100, and the X100S doesn't seem like it'll give me more or less DOF, I'm holding back. But honestly, if I didn't have the X100, I'd have pre-ordered a X100S a long while ago.
Poking through JPSX...